Los Angeles, CA - The investigation into the tragic deaths of Rob Reiner, 78, and his wife Michele Reiner, 70, continues to unfold, with a key focus on their son, Nick Reiner, 32, who has been charged with two counts of first-degree murder. A recent report by The New York Times reveals that Nick Reiner, who has been diagnosed with schizophrenia and schizoaffective disorder, had his medication altered approximately one month before the killings.
Sources with direct knowledge of the case have indicated that the medication change was prompted by Nick experiencing adverse side effects from his previous prescription. While the specifics of the medications involved and the exact reasons for the change remain undisclosed, this alteration in his treatment regimen is being examined as a potential factor in the events leading up to the deaths of his parents.
The TMZ Investigates: The Reiner Murders program on FOX, featured insights suggesting that the change in medication may have significantly impacted Nick's mental state. Harvey Levin of TMZ stated that sources indicated the medication change "literally put him out of his head". He further elaborated that Rob and Michele Reiner were reportedly alarmed by the change in Nick's behavior in the weeks leading up to their deaths but felt helpless in addressing the situation.
Dr. Domenick Sportelli, a psychiatrist who has not treated Nick Reiner, explained to "Extra" that changes in medication for individuals with schizoaffective disorder can be challenging, potentially leading to relapse and decompensation until stability is regained.
Nick Reiner's long-standing struggles with mental health and substance abuse have been well-documented. He has been open about his battles with addiction, revealing that he entered rehab facilities nearly 20 times, beginning in his teenage years. In 2015, Nick co-wrote "Being Charlie," a film about a young man's struggle with drug addiction, which was directed by his father, Rob Reiner.
Following the discovery of Rob and Michele Reiner's bodies in their Brentwood home on December 14, 2025, Nick was taken into custody. Law enforcement officials used cellphone data and surveillance footage to locate him. The Los Angeles County medical examiner's office confirmed that the couple's deaths were the result of "multiple sharp force injuries".
Nick Reiner's arraignment was continued to January 7, 2026, and he was placed under suicide watch. At the arraignment, he wore a blue suicide prevention smock.
The investigation is ongoing, and authorities have not yet disclosed a motive for the killings. Los Angeles County District Attorney Nathan Hochman has stated that a decision on whether to seek the death penalty has not yet been made. Nick Reiner's next court date is set for February 23, 2026.
